HCST, Recombinant, Human, aa20-48, hIgG-His-Tag (Hematopoietic Cell Signal Transducer Isoform 1, HCST, DAP10, KAP10, PIK3AP)

Size

£607.00

SKU:: 396875
Molecular Weight:: 30.1
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Extra Details:: HCST, also known as hematopoietic cell signal transducer isoform 1, is a member of the DAP10 family. It can be part of an immunoreceptor complex. This receptor plays an important role in inducing cytotoxicity against MHC class I chain-associated MICA and target cells expressing cell surface ligands such as MICB and UL16-binding protein (ULBP). This receptor complex can play a role in cell survival and proliferation by activation of NK and T cell responses.Recombinant human HCST, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa20-48 of human HCST, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~30.1kD (271aa), ~28-40kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADPTTPGERS SLPAFYPGTS GSCSGCGSLS LPLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice