Glrx, Recombinant, Mouse, aa1-107, His-Tag (Glutaredoxin-1, D13Wsu156e, Glrx1, Grx1, TTase)

Size

£576.00

SKU:: 396869
Molecular Weight:: 14.3
Purity:: ~95% (SDS-PAGE)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM MES, pH 5.0, 0.1M sodium chloride, 20% glycerol.
Extra Details:: Glrx, also known as glutaredoxin-1, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Mammalian Glutaredoxin is known to have two isoforms, GRX1 and GRX2. GRX1 is a cytosolic protein, whereas GRX2 is localized both in the mitochondria and nucleus. Glrx may be involved in a various cellular events such as signal transduction, stress response, and metabolic regulation by regulating the redox status of cellular proteins. Recombinant mouse Glrx, expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa1-107 of mouse Glrx, expressed in E. coli. Molecular Weight: ~14.3kD (130aa), Confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAQEFVN CKIQSGKVVV FIKPTCPYCR KTQEILSQLP FKQGLLEFVD ITATNNTSAI QDYLQQLTGA RTVPRVFIGK DCIGGCSDLI SMQQTGELMT RLKQIGALQL Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice