RYK (Tyrosine Protein Kinase RYK Precursor, D3S3195, Vik, Tyrosine Protein Kinase RYK, JTK5A Protein Tyrosine Kinase, RYK1, RYK 1, Receptor Like Tyrosine Kinase Precursor, Tyrosine-Protein Kinase RYK, Receptor Like Tyrosine Kinase, ERK 3, RYK, JTK 5A, Hydroxyaryl Protein Kinase, JTK5, JTK5A, RYK HUMAN, Ryk, JTK 5)

Size

£626.00

SKU:: 385056
Application:: WB
Purity:: Purified by peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa150-250 of human RYK, conjugated to KLH.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide, 50% glycerol.
Extra Details:: RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice