Ro3280

Size

£380.00

SKU:: 380363
Molecular Weight:: 543.61
Purity:: ≥98%
Supplier:: United States Biological
CAS Number:: 1062243-51-9
Extra Details:: Ro3280 is a Polo-like kinase 1 (PLK1) inhibitor. Ro3280 shows strong antitumor activity in xenograft mouse models, has good selectivity against other kinases and has excellent in vitro cellular potency. Synonyms: 4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide; 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide CAS Number: 1062243-51-9 Molecular Formula: C₂₇H₃₅F₂N₇O₃ Molecular Weight: 543.61 Purity: 98+% Solubility: Alcohol: 100 mg/mL (183.95 mM); DMSO: 100 mg/mL (183.95 mM); Water: Insoluble