378195
CD30
Size
£767.00
- SKU:
- 378195
- Application:
- IHC-Fr
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Full length recombinant protein corresponding to human CD30. Localization: Cell surface, cytoplasmic
- Clone:
- rKi-1/779 (recomb)
- Format:
- Supplied as a liquid in PBS, 0.1mg/ml BSA, 0.05% sodium azide.
- Extra Details:
- CD30 is synthesized as a 90kD precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kD glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. About one third of the CD30/Ki-1 positive lymphomas lack the leukocyte common antigen (CD45). 378195 distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (formalin-fixed paraffin sections): 0.5-1ug/ml for 30 min at RT Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice