MOCOS (HMCS, MOS, Molybdenum Cofactor Sulfurase)

Size

£685.00

SKU:: 377169
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-888 from human MOCOS. MW of the GST-Tag alone is ~26kD.
Clone:: 2E8
Format:: Supplied as a liquid in PBS, pH 7.4.
Extra Details:: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Sequence: MAGAAAESGRELWTFAGSRDPSAPRLAYGYGPGSLR ELRAREFSRLAGTVYLDHAGATLFSQSQLESFTSDLM ENTYGNPHSQNISSKLTHDTVEQVRYRILAHFHTTAED YTVIFTAGSTAALKLVAEAFPWVSQGPESSGSRFCYLT DSHTSVVGMRNVTMAINVISIPVRPEDLWSAEERGAS ASNPDCQLPHLFCYPAQSNFSGVRYPLSWIEEVKSGR LRPVSTPGKWFVLLDAASYVSTSPLDLSAHQADFVPIS FYKIFGFPTGLGALLVHNRAAPLLRKTYFGGGTASAYL AGEDFYIPRQSVAQRFEDGTISFLDVIALKHGFDTLERL TGGMENIKQHTFTLAQYTYMALSSLQYPNGAPVVRIYS DSEFSSPEVQGPIINFNVLDDKGNIIGYSQVDKMASLY NIHLRTGCFCNTGACQRHLGISNEMVRKHFQAGHVCG DNMDLIDGQPTGSVRISFGYMSTLDDVQAFLRFIIDTRL HSSGDWPVPQAHADTGETGAPSADSQADVIPAVMGR RSLSPQEDALTGSRVWNNSSTVNAVPVAPPVCDVAR TQPTPSEKAAGVLEGALGPHVVTNLYLYPIKSCAAFEV TRWPVGNQGLLYDRSWMVVNHNGVCLSQKQEPRLC LIQPFIDLRQRIMVIKAKGMEPIEVPLEENSERTQIRQSR VCADRVSTYDCGEKISSWLSTFFGRPCHLIKQSSNSQ RNAKKKHGKDQLPGTMATLSLVNEAQYLLINTSSILEL HRQLNTSDENGKEELFSLKDLSLRFRANIIINGKRAFEE EKWDEISIGSLRFQVLGPCHRCQMICIDQQTGQRNQH VFQKLSESRETKVNFGMYLMHASLDLSSPCFLSVGSQ VLPVLKENVEGHDLPASEKHQDVTS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice