369620
Retinoic Acid Receptor Gamma (RARg, NR1B3, RARC, Nuclear Receptor Subfamily 1 Group B Member 3)
Size
£626.00
- SKU:
- 369620
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Retinoic acid receptors are retinoic acid-inducible enhancer factors belonging to the superfamily of steroid/thyroid nuclear receptors. A third type of receptor, Retinoic Acid Receptor Gamma, was first identified in the mouse where its RNA was detected predominantly in skin, a well-known target for retinoic acid. Krust et al. (1989) used mouse cDNA to clone the human counterpart. Comparisons of the amino acid sequences of all 6 human and mouse RARs indicated that the interspecies conservation of a given member of the RAR subfamily, i.e., alpha, beta, or gamma, is much higher than the conservation of all 3 receptors in a given species. These observations indicate that the 3 forms of retinoic acid receptor may perform specific functions. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice