369564
LXRb (Liver X Receptor Beta, NR1-H2, UNR, LXR-B, NER, NER-I, RIP15, Nuclear Receptor Subfamily 1, Group H, Member 2, Ubiquitously-Expressed Nuclear Receptor, Oxysterols receptor LXR-beta)
Size
£537.00
- SKU:
- 369564
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa1-446 from mouse LXRb, expresssed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
- Extra Details:
- Liver X receptor beta (LXR-beta) is a member of the nuclear receptor family of transcription factors. The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins. Shinar et al. (1994) determined that NER encodes a polypeptide of 461aa and contains both the DNA-binding and ligand-binding domains seen in other nuclear receptors. A single 2.3-kb transcript was seen in all cells and tissues tested. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice