NAGA, Recombinant, Human, aa18-411, His-Tag (Alpha-N-acetylgalactosaminidase)

Size

£607.00

SKU:: 369103
Molecular Weight:: 45.5
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Extra Details:: NAGA, also known as alpha-N-acetylgalactosaminidase, is a lysosomal exoglycosidase that cleaves terminal alpha-N-acetylgalactosamine residues from glycopeptides and glycolipids. It is hardly expected to cause an allergic reaction in Fabry disease patients. It is highly promising as a new and safe enzyme for ERT for Fabry disease. Source: Recombinant protein corresponding to aa18-411 from human NAGA, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~45.5kD (400aa) 40-57kD (SDS-PAGE under reducing conditions Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.