Ctss, Recombinant, Mouse, aa21-340, His-Tag (Cathepsin S Isoform 2)

Size

£607.00

SKU:: 369047
Molecular Weight:: 37.2
Purity:: ≥90% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Extra Details:: Ctss, as known as cathepsin S isoform 2, is a lysosomal cysteine protease of the papain family. This protein plays a major role in the processing of the MHC class II-associated invariant chain. It has been implicated in the pathogenensis of several diseases such as Alzheimer s disease and degenerative disorders associated with the cells of the mononuclear phagocytic system. Also, it is less abundant in tissues than Cathepsins B, L and H. The highest levels of this protein have been found in lymph nodes, spleen and phagocytic cells. Source: Recombinant protein corresponding to aa21-340 from mouse Ctss, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~37.2kD (328aa) 28-40KD (SDS-PAGE under reducing conditions) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.