SPZ1 (Spermatogenic Leucine Zipper Protein 1, Testis-specific Protein 1, Testis-specific Protein NYD-TSP1, NYD-TSP1)

Size

£685.00

SKU:: 368348
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: SPZ1 (NP_115956.2, aa1-430) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Clone:: 3D12
Format:: Supplied as a liquid in PBS, pH 7.4.
Extra Details:: Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1:2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression. Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MASSAKSAEMPTISKTLNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKMRSASSLR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice