PKP4 (p0071, Plakophilin 4, Catenin 4)

Size

£800.00

SKU:: 367758
Purity:: Supernatant
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to aa85-104: EKSFPWRSTDVNTGVSKPR, from human Plakophilin 4
Clone:: 7.7.9
Format:: Supplied as a liquid, 0.09% sodium azide.
Extra Details:: p0071 is specific for a subtype of adherens junctions, with a molecular mass of 135kD and is closely related to neurojungin/delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4. Applications: Suitable for use in Immunofluorescence, Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.