CD8 (CD8A, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha, Suppressor/Cytotoxic T Cell)

Size

£262.00

SKU:: 367139
Application:: Flow Cytometry
Purity:: Highly Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human peripheral blood T lymphocytes
Clone:: OKT8
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: CD8 is a 32-34kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD8alpha forms either a homodimer (2 alpha chains) or a heterodimer with CD8beta and is expressed on the surface of cytotoxic T cells, NK cells, cortical thymocytes, and dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. The OKT8 antibody specifically binds the alpha chain of human CD8. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤0.5ug/1x10e6 cells in 100ul of staining volume followed by a secondary florescent conjugated anti‐mouse antibody Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.