366956
HLA Class I (Low Endotoxin, Azide Free)
Size
£672.00
- SKU:
- 366956
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Membrane of human tonsil cells
- Clone:
- W6/32
- Format:
- Supplied as a liquid in PBS, pH 7.4. No preservative added.
- Extra Details:
- HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. 366956 is a valuable reagent for analyzing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. Also suitable as a positive control for HLA tissue typing and crossmatching. Applications: Suitable for use in ELISA, Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Functional Application. Other applications not tested. Recommended Dilution: Flow Cytometry: 1-4ug/ml Immunohistochemistry: frozen Functional Application: suitable as a positive control for HLA tissue typing. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice