LY-411575 (LY 411575, LY411575, Semagacestat)

Size

£527.00

SKU:: 366898
Molecular Weight:: 479.5
Purity:: Highly Purified (~98%)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 209984-57-6
Format:: Supplied as a crystalline solid.
Extra Details:: Synonyms: LY 411575, LY411575, Semagacestat Chemical Name: (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide Molecular Formula: C26H23F2N3O4 Molecular Weight: 479.5 CAS Number: 209984-57-6 Purity: ≥98% Applications: FA Appearance: Crystalline solid Description: LY-411575 is a potent and selective inhibitor of y-secretase, which is involved in APP proteolysis. Via this inhibition, it also blocks Notch activation. LY-411575 is reported to have anti-cancer applications and is capable of promoting goblet cell differentiation in mouse organoids. Storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 60mM.