PCMT1, NT (Protein-L-isoaspartate(D-aspartate) O-Methyltransferase, PIMT, 2.1.1.77, L-isoaspartyl Protein Carboxyl Methyltransferase, Protein L-isoaspartyl/D-aspartyl Methyltransferase, Protein-beta-aspartate Methyltransferase)

Size

£384.00

SKU:: 366849
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa18-55 from human PCMT1 at N-terminal, KLH conjugated. Species sequence homology: bovine, mouse, porcine and rat
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl- terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.