CD274 (B7-H1, PD-L1) (PE)

Size

£242.00

SKU:: 366817
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rat
Clone:: 10F.9G2
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Extra Details:: CD274, also known as B7-H1 or PD-L1, is a 43kD glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤0.25ug/million cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.