365627
ZFHX4 (Zinc Finger Homeobox Protein 4, ZFH4, Zinc finger homeodomain protein 4)
Size
£517.00
- SKU:
- 365627
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Pro189 of human ZFHX4, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- The 1p breakpoint was situated approximately 13 Mb distal to the previously reported linkage locus at 1p34.1-p32 identified by linkage as the site of a gene responsible for congenital bilateral isolated ptosis (PTOS1), and did not disrupt the coding sequence, whereas the chromosome 8 breakpoint disrupted a gene homologous to the mouse zfh4 gene. McMullan et al. (2002) identified 10 exons of the human ZFH4 gene covering approximately 161 kb of DNA; the translocation breakpoint occurred in intron 4. Murine zfh4 codes for a zinc finger homeodomain protein that is a transcription factor expressed in both muscle and nerve tissue. McMullan et al. (2002) proposed that human ZFH4 is a candidate gene for congenital bilateral isolated ptosis. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice