VTN (Vitronectin, V75, VN, VNT, Serum Spreading Factor, Somatomedin B, Complement S-Protein)

Size

£505.00

SKU:: 365583
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Gln21-Arg400 of rat VTN, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: Vitronectin, is a 75kD glycoprotein in plasma and tissue. (S-protein is not to be confused with protein S.) A multifunctional protein, it promotes attachment and spreading of animal cells in vitro, inhibits cytolysis by the complement C5b-9 complex, and modulates antithrombin III-thrombin action in blood coagulation. The primary structure of vitronectin has been deduced from the sequence of its cloned cDNA. Polymorphism of vitronectin of plasma has been demonstrated. Sun and Mosher (1989) demonstrated that the frequencies are different in Orientals and Caucasians. By use of high resolution fluorescence in situ hybridization (FISH), Fink et al. (1992) mapped the VTN gene to 17q11. The localization was confirmed by cohybridization with a centromere-specific alphoid probe. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice