365458
TSK (Tsukushin, E2IG4, TSKU, LRRC54, Tsukushi, E2-induced gene 4 protein, Leucine Rich Repeat Containing 54, Tsukushi Small Leucine Rich Proteoglycan Homolog)
Size
£522.00
- SKU:
- 365458
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Glu30-Gln307 of mouse TSK, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Tsk is a BMP inhibitor in oviparous vertebrates that forms a ternary complex with Bmp and chordin and is involved in the regulation of primitive streak and Hensen node. Using transcript-specific PCR primers for novel sequences that increased more than 10-fold upon treatment with 17-beta estradiol (E2), they cloned 5 cDNAs, designated E2-induced genes (E2IG) 1-5, from a human placenta cDNA library. The E2IG4 cDNA encodes a deduced 353aa protein containing a leucine-rich repeat in the N terminus and 8 additional leucine-rich repeats. E2IG4 demonstrates domain and structural homology to extracellular matrix leucine-rich proteoglycans such as decorin and biglycan. It also contains various potential phosphorylation sites. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice