365400
TOR1B (Torsin 1B, DQ1, Torsin ATPase-1B, Torsin family 1 member B)
Size
£537.00
- SKU:
- 365400
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa83-327 of mouse TOR1B, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- By exon trapping on chromosome 9q34, screening fetal brain, adult frontal cortex, and adult liver cDNA libraries, and 5-prime and 3-prime RACE, Ozelius et al. (1997) cloned TOR1B, which they designated DQ1. The deduced 289aa protein has a calculated molecular mass of more than 32kD. TOR1B shares 69% amino acid identity with TOR1A, and both proteins contain an ATP-binding domain, 2 protein kinase C phosphorylation sites, a casein kinase II phosphorylation site, several N-myristoylation sites, and 6 conserved cysteines. Northern blot analysis detected expression of a 2.8-kb TOR1B transcript in adult brain, but not in fetal brain.TOR1B lies centromeric to TOR1A, and the 2 genes face in opposite orientations with their 3-prime ends about 2 kb apart. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice