365250
TECTb (Tectorin Beta)
Size
£626.00
- SKU:
- 365250
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Lys18-Leu329 of human TECTb, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- The genes for alpha-tectorin and beta-tectorin encode the major noncollagenous proteins of the tectorial membrane of the cochlea.The mouse beta-tectorin gene encodes a 320aa protein containing a hydrophobic secretory signal sequence and 4 potential N-glycosylation sites. Both alpha- and beta-tectorin contain a zona pellucida domain, but otherwise are not homologous.A second group of proteins abundant in the inner ear included 5 additional types of collagen. A third group, including COCH5B2 (COCH) and ear-specific connexin, comprised the proteins whose human equivalents are candidates to account for hearing disorders. This last group also included proteins expressed in 2 cells types unique to the inner ear, homogene cells and cells of the tegmentum vasculosum. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice