365112
SNRPD1 (Small Nuclear Ribonucleoprotein Polypeptide D1, SMD1, SNRP-D1, Sm-D autoantigen, snRNP core protein D1)
Size
£524.00
- SKU:
- 365112
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Arg119 of human SNRPD1, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Small nuclear ribonucleoprotein Sm D1 is a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. A clone was obtained that encoded a predicted 357aa protein with 9 Gly-Arg repeats at its carboxy terminus similar to regions in the Epstein-Barr virus nuclear proteins EBNA-1 and EBNA-2, as well as the yeast transcription factor SNF2. Lehmeier et al. (1994) showed that the D1 amino acid sequence is 29% identical to D3 and less than 15% identical to D2. The authors also showed that sera from 3 patients with lupus erythematosus detected the D1 and D3 components twice and the D2 component 3 times. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- MKLVRFLMKL SHETVTIELK NGTQVHGTIT GVDVSMNTHL KAVKMTLKNR EPVQLETLSI RGNNIRYFIL PDSLPLDTLL VDVEPKVKSK KREAVAGRGR GRGRGRGRGR GRGRGGPRR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice