365083
SLC39A6 (Solute Carrier Family 39, Member 6, LIV-1, Zinc Transporter Protein 6, Estrogen-regulated protein LIV-1, Zrt- and Irt-like protein 6, Zinc transporter ZIP6)
Size
£626.00
- SKU:
- 365083
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Phe29-Trp325 of human SLC39A6, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters. LIV1 contains an N-terminal cleavable signal peptide, a long extracellular N terminus, 6 to 8 transmembrane domains, and a short extracellular C terminus. It has a conserved histidine residue present in ZIP-type zinc transporters, a consensus catalytic zinc-binding motif found in some metalloproteases, and other histidine-rich areas, including several tandem histidine-rich repeats. LIV1 has several protein degradation motifs, including a PEST sequence and a putative ubiquitin pathway degradation signal. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice