365073
SLAMF1 (Signaling Lymphocytic Activation Molecule Family, Member 1, CD150, SLAMF1, CDw150, SLAM, Signaling lymphocytic activation molecule)
Size
£537.00
- SKU:
- 365073
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Leu17-Trp227 of rat SLAMF1, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Tatsuo et al. (2000) found that in MV-resistant cell lines infection with clinical MV and expression of SLAM, but not CD46, caused cytopathic effects (CPE). Likewise, anti-SLAM antibody protected cells from CPE when challenged with MV. Lymphoid cell lines expressing SLAM, but not lymphoid and myelomonocytic cell lines devoid of SLAM, were shown to be susceptible to MV. Tatsuo et al. (2000) noted that the expression of SLAM on activated B and T lymphocytes correlates with the pathology of MV infection in humans and monkeys, in which lymphoid organs are the chief sites of MV replication. They proposed that binding of MV to SLAM may impair the signaling functions of SLAM in lymphocyte activation and inhibit Th0/Th1 cytokine production, thereby promoting Th2 cytokine production. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice