SAA2 (Serum Amyloid A2, SA-A2)

Size

£495.00

SKU:: 364968
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Gly20-Tyr122 of mouse SAA2, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: The 6 sequences, referred to as SAA1, SAA1 des Arg, SAA2-alpha, SAA2-alpha des Arg, SAA2-beta, and SAA2-beta des Arg, are resolved by electrofocusing into 6 isoforms. SAA1 is the product of one gene, while SAA2-alpha and SAA2-beta, which differ by only a single aa, represent allelic sequences of a second gene. Although the first reported AA protein corresponded to SAA2-beta, subsequent analyses showed that the vast majority of the protein isolated from amyloid deposits is derived from SAA1. The SAA2-tat/HIV-sTNFR:Ig construct, and derivatives thereof, may therefore be ideally suited to gene therapy applications that require the local production of potent and specific immune modifiers only when there is active pathology. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGS-G FFSFIGEAFQ GAGDMWRAYT DMKEAGWKDG DKYFHARGNY DAAQRGPGGV WAAEKISDAR ESFQEFFGRG HEDTMADQEA NRHGRSGKDP NYYRPPGLPA KY Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice