364793
PTGES2 (Prostaglandin E Synthase 2, C9orf15, PGES2, mPGES-2, Chromosome 9 Open Reading Frame 15, Microsomal prostaglandin E synthase 2, Prostaglandin E synthase 2 truncated form)
Size
£479.00
- SKU:
- 364793
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Tyr145- Thr357 of human PTGES2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- TGES2 catalyzes the conversion of prostaglandin H2 to prostaglandin E2 (Tanikawa et al). It also activates transcription from a gamma-interferon (IFNG)-activated transcriptional element, or GATE. Tanikawa et al. (2002) identified monkey and human cDNAs encoding proteins homologous to Ptges2 purified from the microsomal fraction of bovine heart. The monkey and human cDNAs encode 377aa proteins that share 97% identity. Both proteins have 87 additional N-terminal aa compared with the purified bovine Ptges2, and they both have a consensus region shared with glutaredoxin and thioredoxin. Hu et al. (2002) cloned mouse Ptges2, which they designated Gbf1. The deduced protein contains 384aa and has a calculated molecular mass of about 38kD. Applications: Suitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 0.001-2ug/ml Immunohistochemistry: 5-20ug/ml Flow Cytometry: 10ug/ml Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- YRKVPI LVAQEGESSQ QLNDSSVIIS ALKTYLVSGQ PLEEIITYYP AMKAVNEQGK EVTEFGNKYW LMLNEKEAQQ VYGGKEARTE EMKWRQWADD WLVHLISPNV YRTPTEALAS FDYIVREGKF GAVEGAVAKY MGAAAMYLIS KRLKSRHRLQ DNVREDLYEA ADKWVAAVGK DRPFMGGQKP NLADLAVYGV LRVMEGLDAF DDLMQHT Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice