PRODH (Proline Dehydrogenase, Mitochondrial, PDH, PIG6, POX2, PRODH1, PRODH2, SCZD4, TP53I6, p53-induced gene 6 protein, L-Proline Dehydrogenase, L-Proline(acceptor)Oxidoreductase, Proline Oxidase 1)

Size

£537.00

SKU:: 364758
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Arg398-Gly551 of mouse PRODH, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Proline dehydrogenase, mitochondrial is a mitochondrial proline dehydrogenase which catalyzes the first step in proline catabolism. Deletion of this gene has been associated with type I hyperprolinemia. The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes: DiGeorge syndrome and CATCH22 syndrome. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with other acceptors.This enzyme participates in arginine and proline metabolism. the two substrates of this enzyme are L-proline and acceptor, whereas its two products are (S)-1-pyrroline-5-carboxylate and reduced acceptor. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry:: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice