364563
PCYOX1 (Prenylcysteine Oxidase 1, PCL1, Prenylcysteine lyase)
Size
£626.00
- SKU:
- 364563
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to yr174-Leu505of human PCYOX1, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product . The deduced 505aa protein contains a predicted signal sequence, several transmembrane regions, and potential N-glycosylation sites. Northern blot analysis detected a 6-kb transcript in heart, kidney, liver, colon, placenta, skeletal muscle, and pancreas, with low expression in brain and no expression in spleen. The 3-prime untranslated region contains several SINEs, including Alu and MIR sequences. The predicted protein has 506aa. RT-PCR ELISA detected high to moderate expression in all adult and fetal human tissues and all specific brain regions tested. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice