364487
OIT3 (Oncoprotein Induced Transcript 3, LZP, Liver-specific zona pellucida domain-containing protein)
Size
£524.00
- SKU:
- 364487
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Val297-Arg506 of human OIT3, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- OIT3 contains one EGF-like domain and one ZP domain. It may be involved in hepatocellular function and development. OIT3 is liver-specific and is expressed only in the hepatocytes; down-regulated in hepatocellular carcinoma (HCC) and HCC cell lines. LZP contains an N-terminal signal peptide, followed by 3 epidermal growth factor (EGF)-like domains and a zona pellucida (ZP) domain in its C-terminal region. LZP also contains several N-glycosylation sites. The 546aa mouse Lzp protein shares 89% identity with human LZP. Northern blot analysis of several human tissues detected a 2.4-kb transcript only in liver. Northern blot analysis of whole mouse embryos detected 2 Lzp variants that differed in the length of the UTR and the poly(A) signal used. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice