364445
NUDC (Nuclear Distribution Gene C Homolog, HNUDC, MNUDC, NPD011)
Size
£626.00
- SKU:
- 364445
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala167-Ser298 of human NUDC, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- NudC was first identified as a regulator of nuclear movement in the asexual reproductive cycle of the filamentous fungus Aspergillus nidulans. Human NUDC is a nuclear movement protein that associates with dynein. The deduced 331aa protein contains a basic stretch from lys68 to arg76, an acidic region from asp144 to asp155, and a 94aa C terminus that is highly homologous to A. nidulans NudC. Human NUDC shares 94% and 95% amino acid identity with mouse and rat NudC, respectively. Expression was primarily cytoplasmic, although punctate nuclear staining was also observed. In cultured human erythroid cells, NUDC mRNA and protein were highly expressed in rapidly proliferating cells and declined upon terminal differentiation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice