364432
NT4 (Neurotrphin 4, NT5, NTF4, NT-4/5, Neurotrophic Factor 4, Neurotrophin-5)
Size
£482.00
- SKU:
- 364432
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa81-210 of human NT4, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Neurotrophin-4 (NT-4) like BDNF, is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. It is also known as NT4, NT5, NTF4, and NT-4/5. Differentiation, survival, and function of neurons in vertebrates are controlled by multiple, target-derived neurotrophic factors. The best characterized mammalian neurotrophic factors are 4 structurally related 13- to 14kD basic proteins known as neurotrophinsBerkemeier et al. (1992) identified a cluster of genes on human chromosome 19 that includes neurotrophin-5 (NT5) and 3 pseudogenes, designated NTF6A, NTF6B, and NTF6G. The NTF5 and NTF6 gene loci were mapped to chromosome 19 by Southern analysis of somatic cell hybrid panels. In the mouse, the Ntf5 gene was assigned to chromosome 7. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice