364404
NOX5 (Nicotinamide Adenine Dinucleotide Phosphate Oxidase 5, NOX5A, NOX5B, NOX5-A, NOX5-B, NADPH Oxidase,EF-Hand Calcium Binding Domain 5)
Size
£479.00
- SKU:
- 364404
- Application:
- IHC-Fr
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa456-765 of human NOX5, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- NOX5 is distantly related to the gp91-phox subunit of the phagocyte NADPH oxidase with conserved regions crucial for electron transport (NADPH, FAD, and heme binding sites). However, NOX5 has a unique N-terminal extension that contains 3 EF-hand motifs. Banfi et al. (2001) demonstrated 2 NOX5 isoforms of 737 and 719aa designated NOX5A and NOX5B, respectively. Northern blot analysis demonstrated restricted expression of an approximately 2.7-kb NOX5A transcript in spleen and an approximately 2.9-kb NOX5B transcript in testis. In situ hybridization localized NOX5 in pachytene spermatocytes of testis and in B- and T-lymphocytic-rich areas of spleen and lymph nodes. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice