364367
NKR2B4 (Natural Killer Cell Receptor 2B4, CD244, 2B4, NAIL, NKR2-B4, Nmrk, SLAMF4, NK cell activation-inducing ligand, Signaling lymphocytic activation molecule 4)
Size
£495.00
- SKU:
- 364367
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser26-Thr212 of mouse NKR2B4, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- 2B4, called also NKR2B4 [natural killer cell receptor 2B4] has been identified originally on mouse NK-cells and subsets of T-cells mediating nonMHC restricted cell killing. Murine NK-cells express two alternatively spliced isoforms, designated 2B4-S and 2B4-L. 2B4-S functions as an activating receptor, whereas 2B4-L is inhibitory. The new designation of this protein is CD244. The 2B4 protein is expressed on all NK-cells, a subset of CD8(+) T-cells, basophils, mast cells, and monocytes. 2B4 is considered to be an activating receptor because cross-linking of 2B4 on NK-cells with a monoclonal antibody leads to NK-cell activation in vitro. However, 2B4 can also act as an inhibitory signaling receptor for NK-cells. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice