364319
NCR1 (Natural Cytotoxicity Triggering Receptor 1, CD335, NCR1, LY94, NK-P46, NKP46, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein)
Size
£495.00
- SKU:
- 364319
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Gln17-Thr211 of mouse NCR1, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Natural cytotoxicity triggering receptor 1 is a protein encoded by the NCR1 gene. By screening a human NK cell cDNA library, Pessino et al. (1998) cloned the cDNA for NKp46, or LY94, an Ig superfamily member that may cooperate with other activating receptors. The LY94 cDNA encodes a 304aa type I transmembrane protein. The extracellular region is preceded by a 21-residue signal peptide with 2 cysteine-bridged C2-type Ig-like domains. A stem connects the extracellular domain to the apparently short transmembrane domain of 19 aa, which includes an arginine. The intracellular region contains 30aa and is rich in basic residues, but does not contain any immunoreceptor tyrosine-based activating motifs (ITAM). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice