364316
NCK1 (Non Catalytic Region Of Tyrosine Kinase Adaptor Protein 1, NCKalpha, NCKa, NCK adaptor protein 1, Cytoplasmic protein NCK1, SH2/SH3 adaptor protein NCK-alpha)
Size
£626.00
- SKU:
- 364316
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala2-Ser377 of human NCK1, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- The Cytoplasmic protein NCK1 Protein belongs to the adaptor family of proteins. The Nck family has two known members in human cells.(Nck-1/Nckalpha and NcK2/NcKbeta), two in mouse cells(mNckalpha and mNckbeta/Grb4) and one in drosophila( Dock means dreadlocks-ortholog). The two murine gene products exhibits 68% aminoacid identity to one another,with most of the sequence variation being located to the linker regions between the SH3 and SH2 domains, and are 96% identical to their human counterparts. While human nck-1 gene has been localised to the 3q21 locus of chromosome 3,the nck-2 genecan be found on chromosome 2 at the 2q12 locus. The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice