364305
NCAM2 (Neural Cell Adhesion Molecule 2, NCAM21)
Size
£626.00
- SKU:
- 364305
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Leu21-Gln297 of human NCAM2, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Paoloni-Giacobino et al. (1997) performed exon trapping from chromosome 21-specific cosmids. They identified a novel trapped exon that showed homology to NCAM1. They cloned the corresponding cDNA from a human fetal brain cDNA library and reported that it encodes an 837aa polypeptide containing 5 immunoglobulin-like domains, 2 fibronectin type III domains, and 1 predicted transmembrane domain. The overall size and structure of the predicted protein are similar to the shorter isoform of NCAM1. The authors were unable to identify any longer cDNAs. Paoloni-Giacobino et al. (1997) showed by Northern blot analysis that the NCAM2 gene is expressed as mRNAs of 9.5 and 4.4 kb in fetal and adult brain; they observed these and other transcript sizes at lower levels in several other tissues. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice