364245
MUC13 (Mucin 13, Cell Surface Associated, DRCC1, RECC, Down-Regulated In Colon Cancer 1)
Size
£517.00
- SKU:
- 364245
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser174-Gln404 of human MUC13, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- The rodent and human MUC13 cDNAs contain a series of CA dinucleotide repeats and an alternative polyadenylation signal. The deduced 512aa human protein has a calculated molecular mass of 54.7kD. Both human and rodent MUC13 have an N-terminal signal peptide, followed by a serine/threonine-rich mucin repeat domain, a cysteine-rich EGF-like domain, a SEA module, 2 more cysteine-rich EGF-like domains, a transmembrane region, and a cytoplasmic tail. The mucin repeat domain is predicted to be heavily O-glycosylated, and MUC13 also has sites for N-glycosylation and phosphorylation. Northern blot analysis detected highest expression of a 3.2-kb transcript in colon and trachea, with moderate levels in kidney, small intestine, appendix, and stomach, and low levels in several other tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice