MEP1a (Meprin A Alpha, PPHA, PABA Peptide Hydrolase, Endopeptidase-2, N-benzoyl-L-tyrosyl-P-amino-Benzoic Acid Hydrolase Subunit Alpha, PABA Peptide Hydrolase)

Size

£482.00

SKU:: 364109
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to His213-Val506 of human MEP1a, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: Meprins, members of the 'astacin family' of metalloendopeptidases, are capable of hydrolyzing a variety of peptide and protein substrates. Two forms of meprins, designated A and B. Meprin A (EC 3.4.24.18) is the best characterized of the meprins and is known to hydrolyze peptides such as bradykinin, melanocyte-stimulating hormone, neurotensin, luteinizing hormone releasing hormone, transforming growth factor-alpha, and parathyroid hormone. Meprin B from mouse kidney has latent proteolytic activity against polypeptide substrates. Rat meprin A is sometimes referred to as endopeptidase-2 or endopeptidase-24.18; human meprin A is also called N-benzoyl-L-tyrosyl-p-aminobenzoic acid (PABA peptide) hydrolase (PPH). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice