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364031

LYPLA1 (Lysophospholipase I, APT1, LPL1, LYSOPLA, Acyl-Protein Thioesterase 1)

Size

£537.00

SKU:
364031
Purity:
Purified by Protein A and peptide affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Met1-Asp230 of mouse LYPLA1, expressed in E. coli.
Format:
Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:
Lysophospholipids (LysoPLs) are detergent-like intermediates in phospholipid metabolism. Increased LysoPL levels have been detected in a variety of diseases including atherosclerosis and hyperlipidemia. In some cases, increased levels of LysoPLs are hypothesized to result from a dysfunction of LysoPL-regulating enzymes including lysophospholipases, which act on biologic membranes to regulate the level of LysoPLs by hydrolysis. Acyl-protein thioesterase 1 hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice