364016
LSP1 (Lymphocyte Specific Protein 1,WP34, pp52, 47kD actin-binding protein, 52kD phosphoprotein, Lymphocyte-specific antigen WP34)
Size
£577.00
- SKU:
- 364016
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ser127-Pro331 of rat LSP1, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- Lymphocyte-specific protein 1 is an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. May et al. (1993) and others used various cDNA cloning strategies to identify genes preferentially expressed in B lymphocytes. One gene, variously named LSP1 and pp52, exhibited a number of properties supporting a possible role in B-cell signaling pathways. The gene codes for a 52kD phosphoprotein expressed only in transformed and untransformed B cells, thymocytes, and untransformed T-cell lines. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice