363970
LIMCH1 (LIM And Calponin Homology Domains Containing Protein 1, LIMCH1A, LMO7B)
Size
£522.00
- SKU:
- 363970
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Glu21-Asn125 of mouse LIMCH1 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- LIMCH1 contains one CH (calponin-homology) domain and one LIM zinc-binding domain. There are nine named isoforms. The calponin homology (CH) domain is a protein module of about 100 residues that was first identified at the N-terminal of calponin, an actin-binding protein playing a major regulatory role in muscle contraction. Three major groups of CH-domain-containing proteins have been recognized on the basis of sequence analysis. Proteins containing a single N-terminal CH domain (1xCH proteins) include calponin itself as well as signaling proteins such as Vav, IQGAP and Cdc24. Proteins with an F-actin-binding domain (ABD) composed of two CH domains in tandem (2xCH proteins) include spectrins, dystrophin, filamins and plakins. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice