363932
LDB1 (LIM Domain Binding Protein 1, CLIM2, NLI, C-Terminal LIM Domain Protein 2, LIM domain-binding factor CLIM2, Nuclear LIM interactor)
Size
£626.00
- SKU:
- 363932
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa112-411 of human LDB1 expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- CLIM1 and CLIM2 have a very high level of identity to each other and to the homologs in other species.CLIM2 encodes a 375aa protein.human LMO2 interacted with human BEX2. Electrophoretic mobility shift assays showed that BEX2 and LMO2 were part of a DNA-binding complex that recognized the E-box element. Other components of this complex included NSCL2 (NHLH2) and LDB1. LDB1 associated with a complex containing LMO4, CTIP, and BRCA1 in transfected human embryonic kidney cells.LDB1 was consistently enriched in the superior temporal gyrus posterior temporal cortex, and perisylvian cortex. LDB1 may be involved in asymmetric patterning of the developing human cortex. Applications: Suitable for use in Western Blot and Immunofluorescence/Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.01-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice