363792
ITGb3 (Integrin Beta 3, CD61, ITG-B3, GP3A, GP3-A, GpIIIa, Platelet Membrane Glycoprotein IIIa)
Size
£495.00
- SKU:
- 363792
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Asp135-Ile377 of mouse ITGb3 fused to His-Tag and S-tag at N-terminal expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- CD61 is a cluster of differentiation found on thrombocytes. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. The platelet and endothelial cell heterodimers use GP IIIa as the beta subunit; the leukocyte heterodimers contain a beta subunit with a molecular mass of 95kD that is homologous to GP IIIa but is clearly a different protein; and the fibronectin receptors contain a beta subunit that appears to be analogous to band 3 of integrin. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice