INPP4A (Inositol Polyphosphate-4-Phosphatase Type I 107k, INPP4, Inositol polyphosphate 4-phosphatase type I, Type I inositol 3,4-bisphosphate 4-phosphatase)

Size

£517.00

SKU:: 363736
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Met1-Thr137 of human INPP4A, expressed in E. coli.
Format:: Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:: INPP4A encodes the inositol polyphosphate 4-phosphatase type I, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. A PCR product was obtained and used to isolate a 5607-bp composite cDNA which encodes a 939aa reading frame from the rat. The authors screened a human brain cDNA library and identified a sequence that predicts a 938aa protein which is 97% identical to the rat protein. Recombinant protein was shown to have the appropriate enzymatic activity. In the rat, the gene is widely expressed with highest levels in the brain, heart, and skeletal muscle. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice