INHbE (Inhibin Beta E, INH-bE, Activin beta-E chain)

Size

£581.00

SKU:: 363734
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to Ser102-Val344 of mouse INHbE expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: INHBE is a member of the activin beta family that plays a role in pancreatic exocrine cell growth and proliferation. Hashimoto et al. cloned INHBE, which they called activin beta-E subunit. The deduced 350aa protein contains an N-terminal hydrophobic signal peptide and a potential N-glycosylation site. The proposed cleavage site at aa232-236 would yield a mature 114aa protein. INHBE shares 97% and 96% similarity with the mouse and rat activin beta-E orthologs, respectively. The deduced mature human beta-E subunit shares aa identity of 44%, 48%, and 64% with activin beta-A, activin beta-B, and activin beta-C, respectively. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. AA Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-STSTYRSML TFQLSPLWSH HLYHARLWLH VPPSFPGTLY LRIFRCGTTR CRGFRTFLAE HQTTSSGWHA LTLPSSGLRS EDSGVVKLQL EFRPLDLNST AAGLPRLLLD TAGQQRPFLE LKIRANEPGA GRARRRTPTC EPETPLCCRR DHYVDFQELG WRDWILQPEG YQLNYCSGQC PPHLAGSPGI AASFHSAVFS LLKANNPWPA GSSCCVPTAR RPLSLLYLDH NGNVVKTDVP DMVV Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice