363664
IL1e (Interleukin 1 Epsilon, IL1F6, IL36a, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), Interleukin 36, Alpha, Interleukin 1 Family, Member 6)
Size
£626.00
- SKU:
- 363664
- Application:
- WB
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Met1-Phe158 of human IL1e, expressed in E. coli.
- Format:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Extra Details:
- The cytokine interleukin-1 (IL1) elicits a wide array of biologic activities that initiate and promote the host response to injury or infection by activating a set of transcription factors, including NFKB and AP1, which in turn induce production of effectors of the inflammatory response. By searching an EST database for sequences resembling IL1 and probing a human genomic library, Smith et al. (2000) identified a cDNA encoding IL1F6, which they designated FIL1-epsilon. The deduced 158aa protein, like FIL1-delta, contains neither a signal peptide nor a prodomain. It shares 48% sequence identity with FIL1-eta. PCR analyses detected expression in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Modeling indicated that FIL1-epsilon has a conserved 12-stranded beta-trefoil structure. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice