363643
IL17B (Interleukin 17B, IL-20, Cytokine Zcyto7, Neuronal interleukin-17-related factor)
Size
£524.00
- SKU:
- 363643
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Gln21-Phe180 of human IL17B, expressed in E. coli.
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Interleukin-17 (IL17) is a T cell-derived cytokine that may play an important role in the initiation or maintenance of the proinflammatory response. Shi et al. (2000) cloned a cDNA encoding IL17B, which they initially designated IL20. The deduced 184aa protein, 88% identical to the mouse sequence, has a 20aa leader sequence, 1 potential N-glycosylation site, and 8 cysteine residues. Northern blot analysis detected a 1.0-kb transcript in spinal cord, testis, and small intestine, with less pronounced expression in prostate, colon mucosal lining, and ovary. SDS-PAGE analysis determined that IL17B is expressed as 23-, 22-, and 18-kD proteins under reducing conditions. Size-exclusion analysis suggested that IL17B is a nondisulfide-linked dimer. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice