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363576

IFNg (Interferon Gamma, IFN-G, IFG, IFI, INFr, IFN, Immune Interferon)

Size

£537.00

SKU:
363576
Purity:
Purified by Protein A and peptide affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa24-166 of canine IFNg, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Extra Details:
Interferon gamma (IFN-gama ) is a multifunctional protein first observed as an antiviral activity in cultures of Sindbis virus-infected leukocytes stimulated by PHA. Produced by T lymphocytes and natural killer (NK) cells, IFN-gamma is now known to be both an inhibitor of viral replication and a regulator of numerous immunological functions. IFN-gamma influences the class of antibody produced by B cells, upregulates class I and II MHC complex antigens and increases. the efficiency of macrophage-mediated killing of intracellular parasites. Most of the activities attributed to IFN-gamma are believed to be mediated by IFN-gamma-induced proteins. The appearance of such proteins is a consequence of IFN-gamma binding to a specific receptor that is distinct from the receptor for IFN-alpha and beta. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-2ug/ml Immunocytochemistry: 5-20ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice