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363570

IFNa2 (Interferon Alpha 2, IFNA2A, IFNA2B, IFNA2C, LeIF A, Alpha-2a Interferon, Interferon Alpha 2b, Interferon Alpha A)

Size

£495.00

SKU:
363570
Purity:
Purified by Protein A and peptide affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa24-192 of rat IFNa2, expressed in E. coli.
Format:
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:
The successful use of intranasal alpha-2-interferon produced by recombinant DNA technology in the prophylaxis of the common cold was reported by Douglas et al. (1986) and Hayden et al. (1986). Ezekowitz et al. (1992) demonstrated the usefulness of recombinant alpha-interferon (interferon alfa-2a) for inducing regression of life-threatening corticosteroid-resistant hemangiomas in infancy. The hemangiomas treated were those that impair the function of vital structures or cause life-endangering complications such as thrombocytopenic coagulopathy with giant hemangioma. The authors concluded that adjuvant recombinant IFN alfa-2b treatment given before or at the time of enucleation might be a treatment option for patients with uveal melanoma with high-risk factors for developing metastatic disease. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice